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| Johnny Depp | Inspector Frederick Abberline | |
| Heather Graham | Mary Kelly | |
| Ian Holm | Sir William Gull | |
| Robbie Coltrane | Sergeant Peter Godley | |
| Ian Richardson | Sir Charles Warren | |
| Jason Flemyng | Netley / the Coachman | |
| Katrin Cartlidge | Dark Annie Chapman | |
| Terence Harvey | Benjamin 'Ben' Kidney | |
| Susan Lynch | Liz Stride | |
| Paul Rhys | Dr. Ferral | |
| Lesley Sharp | Kate Eddowes | |
| Estelle Skornik | Ada | |
| Nicholas McGaughey | Officer Bolt | |
| Annabelle Apsion | Polly Nichols | |
| Joanna Page | Ann Crook | |
| Jason Flemyng | Netley / the Coachman | |
| Mark Dexter | Albert Sickert | |
| Danny Midwinter | Constable Withers | |
| Samantha Spiro | Martha Tabram | |
| David Schofield | McQueen | |
| Bryon Fear | Robert Best | |
| Peter Eyre | Lord Hallsham | |
| Cliff Parisi | Mac Bartender | |
| Sophia Myles | Victoria Abberline | |
| Ralph Ineson | Gordie | |
| Amy Huck | Gull's Maid |
| Regisseur |
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| Producent |
Allen Hughes
Albert Hughes Thomas M. Hammel Jane Hamsher |
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| Schrijver |
Terry Hayes
Rafael Yglesias Alan Moore Eddie Campbell |
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| Camerawerk |
Peter Deming
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| Muzikant |
Trevor Jones
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Frederick Abberline is an opium-huffing inspector from Scotland Yard who falls for one of Jack the Ripper's prostitute targets in this Hughes brothers adaption of a graphic novel that posits the Ripper's true identity. |
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