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| Tom Jane | Carter Blake | |
| Saffron Burrows | Dr. Susan McAlester | |
| Samuel L. Jackson | Russell Franklin | |
| Jacqueline McKenzie | Janice Higgins | |
| Michael Rapaport | Tom Scoggins | |
| Stellan Skarsgård | Jim Whitlock | |
| LL Cool J | Preacher | |
| Aida Turturro | Brenda Kerns | |
| Cristos | Boat Captain | |
| Daniel Rey | Helicopter Pilot | |
| Valente Rodriguez | Helicopter Co-Pilot | |
| Brent Roam | Helicopter Winch Operator | |
| Eyal Podell | Boy #1 | |
| Erinn Bartlett | Girl #1 | |
| Dan Thiel | Boy #2 | |
| Sabrina Geerinckx | Girl #2 | |
| Tajsha Thomas | Friend of Janice | |
| Frank Welker | Parrot Sounds | |
| Mary Kay Bergman | The Parrot | |
| Ronny Cox | Executive - Franklin's Boss | |
| Renny Harlin | Worker | |
| Sarah Kelly | Shark Victim | |
| Roark Loedy | Aqautica Dock Hand |
| Regisseur |
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| Producent |
Bruce Berman
Akiva Goldsman |
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| Schrijver |
Wayne Powers
Donna Powers Duncan Kennedy |
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| Camerawerk |
Stephen F. Windon
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| Muzikant |
Trevor Rabin
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Researchers on the undersea lab Aquatica have genetically altered the brains of captive sharks to develop a cure for Alzheimer's disease. But there's an unexpected side effect: the sharks got smarter, faster, and more dangerous. After a big storm damages their remote research facility, they must fight for their lives. |
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